MetExplore - Metabolomic data mapping

Identifiers
Mapping
Goal

How to map metabolomics data in MetExplore using identifiers (KEGG, or model identifiers) ?

At the end of the course, you will be able to :

  • Find metabolite identifiers
  • Map metabolites in MetExplore
Prerequisites

No particular knowledge required.

Introduction

Mapping metabolites in metabolic networks consist in establishing a link between a measured molecule and its counterpart in the network. The challenge is that network and metabolomics databases are not necesseraly using the same conventions to identify metabolites. There is thus a preliminary step consisting in finding right identifiers for each metabolite of a metabolic fingerprint. Then data can be uploaded in MetExplore to see where they stand in the network.
 

Summary

The slideshow will present the challenge of identifiers through examples. It will indroduce the concept of mapping.

Contents
Conclusion

This course allowed to discover the issue of metabolomics data mapping and in particular the lack of shared identifiers and models. It is now possible to map data in networks. The next step is the use of this mapping in order to identify metabolic pathways of interest.

References